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While no clinical trials have firmly established its efficacy or safety in humans, the volume of in-vitro and animal model data provides a compelling rationale for its continued investigation

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As for the appearance and health of the skin, the antimelanogenetic and anti-age effect of glutathione has been proven by studies : in subjects who took this amino acid orally for 12 weeks, a significant improvement in skin characteristics was observed, including melanin index, reduction of UV spots, a reduction in wrinkles and an increase of skin elasticity compared to those taking placebo pills